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--- en:thymus [2023/07/05 07:38] – brahmantra
+++ en:thymus [] () – - () 127.0.0.1
@@ 1: / 1: @@
-====== Thymus ======
-{{:histology:thymus.png?500px}}
-  * Composed of epithelial cells (endoderm, important for T lymphocyte differentiation), Hassall corpuscles (regressed epithelial cells), T cells of varying phenotypes; B cells in thymic medulla and thymic perivascular space (increase with age, Hum Pathol 2001;32:926); also interdigitating reticulum cells, Langerhans cells, mast cells, eosinophils, stromal cells
-  * Dendritic cells modulate autoimmune regulation through tissue restricted antigens (TSA) and promote central tolerance in thymus (Am J Pathol 2010;176:1104)
-  * Wnt4 regulates thymic cellularity through expansion of thymic epithelial cells and early thymic progenitors.

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